Targeting phosphorylation of STAT3 delays tumor growth in HPV-negative anal squamous cell carcinoma mouse model

Abstract Although conventional chemoradiotherapy is effective for most anal squamous cell carcinoma (ASCC) patients, HPV-negative ASCC patients respond poorly to this treatment and new therapeutic approach is required. Our group has previously established an HPV-negative ASCC mouse model and demonst...

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Bibliographic Details
Main Authors: Lin-Lin Bu, Yi-Cun Li, Guang-Tao Yu, Jian-Feng Liu, Wei-Wei Deng, Wen-Feng Zhang, Lu Zhang, Zhi-Jun Sun
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06643-9