Interleukin-34 and immune checkpoint inhibitors: Unified weapons against cancer

Interleukin-34 and immune checkpoint inhibitors: Unified weapons against cancer

Interleukin-34 (IL-34) is a cytokine that is involved in the regulation of immune cells, including macrophages, in the tumor microenvironment (TME). Macrophages are a type of immune cell that can be found in large numbers within the TME and have been shown to have a role in the suppression of immune...

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Bibliographic Details
Main Authors: Fadhl Alshaebi, Mohammed Safi, Yousif A. Algabri, Mahmoud Al-Azab, Abdullah Aldanakh, Mohammed Alradhi, Alariqi Reem, Caiqing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
immune checkpoint inhibitors (ICIs)
interluikin-34 (IL-34)
tumor microenvironment
programmed cell death protein 1 (PD-1)
cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)
cancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1099696/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1099696/full

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