Metformin limits apoptosis in primary rat cortical astrocytes subjected to oxygen and glucose deprivation
Metformin, a type 2 anti-diabetic drug and an activator of AMP-activated protein kinase (AMPK), has been shown to reduce infarct size and pathological changes affecting astroglia in animal models of ischemic stroke. In this study, we evaluated how metformin affects cell viability, apoptosis and dete...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2018-12-01
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| Series: | Folia Neuropathologica |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Metformin-limits-apoptosis-in-primary-rat-cortical-astrocytes-subjected-to-oxygen-and-glucose-deprivation,20,34468,1,1.html |