Nix-mediated mitophagy regulates platelet activation and life span

Abstract: Platelet activation requires fully functional mitochondria, which provide a vital energy source and control the life span of platelets. Previous reports have shown that both general autophagy and selective mitophagy are critical for platelet function. However, the underlying mechanisms rem...

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Bibliographic Details
Main Authors: Weilin Zhang, Qi Ma, Sami Siraj, Paul A. Ney, Junling Liu, Xudong Liao, Yefeng Yuan, Wei Li, Lei Liu, Quan Chen
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920306315