Reinduction of Hedgehog Inhibitors after Checkpoint Inhibition in Advanced Basal Cell Carcinoma: A Series of 12 Patients

Reinduction of Hedgehog Inhibitors after Checkpoint Inhibition in Advanced Basal Cell Carcinoma: A Series of 12 Patients

For patients with advanced basal cell carcinoma (aBCC) first-line treatment with hedgehog inhibitors (HHIs) and second-line treatment with PD1 inhibitors (PD1i) is available, offering combination and sequencing options. Here, we focus on the efficacy and safety of HHI reinduction after PD1i failure....

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Bibliographic Details
Main Authors: Viola K. DeTemple, Jessica C. Hassel, Michael M. Sachse, Imke Grimmelmann, Ulrike Leiter, Christoffer Gebhardt, Julia Eckardt, Claudia Pföhler, Yenny Angela, Hanna Hübbe, Ralf Gutzmer
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
advanced basal cell carcinoma
hedgehog inhibitor reinduction
sequential treatment
checkpoint inhibition
Online Access:https://www.mdpi.com/2072-6694/14/21/5469

Internet

https://www.mdpi.com/2072-6694/14/21/5469

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