Genotypic analysis of Asp299Gly and Thr399Ile polymorphisms of TLR4 in Egyptian patients with rheumatoid arthritis and systemic lupus
Background Toll-like receptors (TLRs) are essential molecules of the innate immune system that stimulate numerous inflammatory pathways and harmonize systemic defense against a wide array of pathogens. TLRs may also recognize a number of self-proteins and endogenous nucleic acids. Inappropriate sti...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2014-01-01
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Series: | The Egyptian Journal of Internal Medicine |
Subjects: | |
Online Access: | http://www.esim.eg.net/article.asp?issn=1110-7782;year=2014;volume=26;issue=1;spage=15;epage=20;aulast=Taha |