Genotypic analysis of Asp299Gly and Thr399Ile polymorphisms of TLR4 in Egyptian patients with rheumatoid arthritis and systemic lupus

Background Toll-like receptors (TLRs) are essential molecules of the innate immune system that stimulate numerous inflammatory pathways and harmonize systemic defense against a wide array of pathogens. TLRs may also recognize a number of self-proteins and endogenous nucleic acids. Inappropriate sti...

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Bibliographic Details
Main Authors: Hanan A. Taha, Rania E. Sheir, Sanaa S Abdel Shafy, Lamya M. Mohamed
Format: Article
Language:English
Published: SpringerOpen 2014-01-01
Series:The Egyptian Journal of Internal Medicine
Subjects:
Online Access:http://www.esim.eg.net/article.asp?issn=1110-7782;year=2014;volume=26;issue=1;spage=15;epage=20;aulast=Taha