Downregulation of amphiregulin improves cardiac hypertrophy via attenuating oxidative stress and apoptosis

Downregulation of amphiregulin improves cardiac hypertrophy via attenuating oxidative stress and apoptosis

Abstract Amphiregulin (AREG) is a ligand of epidermal growth factor receptor and participates in the fibrosis of multiple organs. However, whether AREG can regulate hypertrophic cardiomyopathy is not well known. This research aims to explore the effect of AREG on cardiac hypertrophy, and whether the...

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Bibliographic Details
Main Authors: Mingyue Ji, Yun Liu, Zhi Zuo, Cheng Xu, Li Lin, Yong Li
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Biology Direct
Subjects:
Amphiregulin
Cardiac hypertrophy
Oxidative stress
Apoptosis
Online Access:https://doi.org/10.1186/s13062-022-00334-w

Internet

https://doi.org/10.1186/s13062-022-00334-w

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