Excessive rest time during active phase is reliably detected in a mouse model of myotonic dystrophy type 1 using home cage monitoring

Excessive rest time during active phase is reliably detected in a mouse model of myotonic dystrophy type 1 using home cage monitoring

Myotonic dystrophy type 1 (DM1) is a dominantly inherited neuromuscular disease caused by the abnormal expansion of CTG-repeats in the 3′-untranslated region of the Dystrophia Myotonica Protein Kinase (DMPK) gene, characterized by multisystemic symptoms including muscle weakness, myotonia, cardio-re...

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Bibliographic Details
Main Authors: Elisabetta Golini, Mara Rigamonti, Marcello Raspa, Ferdinando Scavizzi, Germana Falcone, Genevieve Gourdon, Silvia Mandillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
DVC®
DMSXL
DM1
digital biomarker
sleep
excessive daytime sleepiness (EDS)
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1130055/full

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https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1130055/full

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