Developing Bi-Gold Compound BGC2a to Target Mitochondria for the Elimination of Cancer Cells

Developing Bi-Gold Compound BGC2a to Target Mitochondria for the Elimination of Cancer Cells

Reactive oxygen species (ROS) homeostasis and mitochondrial metabolism are critical for the survival of cancer cells, including cancer stem cells (CSCs), which often cause drug resistance and cancer relapse. Auranofin is a mono-gold anti-rheumatic drug, and it has been repurposed as an anticancer ag...

Full description

Bibliographic Details
Main Authors: Qingbin Cui, Wenwen Ding, Panpan Liu, Bingling Luo, Jing Yang, Wenhua Lu, Yumin Hu, Peng Huang, Shijun Wen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
gold complex
anticancer
TrxR
mitochondria
energy metabolism
Online Access:https://www.mdpi.com/1422-0067/23/20/12169

Internet

https://www.mdpi.com/1422-0067/23/20/12169

Similar Items