Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms

Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms

Bullous pemphigoid is an autoimmune blistering disease caused by autoantibodies targeting BP180 and BP230. While deposits of IgG and/or complement along the epidermal basement membrane are typically seen suggesting complement -mediated pathogenesis, several recent lines of evidence point towards com...

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Bibliographic Details
Main Authors: Connor Cole, Keshavamurthy Vinay, Luca Borradori, Kyle T. Amber
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
bullous pemphigoid
complement - immunological terms
autoimmune blistering diseases
eosinophils – immunology
igE (Immunoglobulin E)
BP180
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.912876/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.912876/full

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