Host genetic factors and vaccine-induced immunity to hepatitis B virus infection.

Vaccination against hepatitis B virus infection (HBV) is safe and effective; however, vaccine-induced antibody level wanes over time. Peak vaccine-induced anti-HBs level is directly related to antibody decay, as well as risk of infection and persistent carriage despite vaccination. We investigated t...

Full description

Bibliographic Details
Main Authors: Branwen J Hennig, Katherine Fielding, John Broxholme, Mathurin Diatta, Maimuna Mendy, Catrin Moore, Andrew J Pollard, Pura Rayco-Solon, Giorgio Sirugo, Marianne A van der Sande, Pauline Waight, Hilton C Whittle, Syed M Zaman, Adrian V Hill, Andrew J Hall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2268746?pdf=render