HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation

HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation

High-risk human papillomavirus (HPV) infection play an important role in the development of lung cancer. Our previously study showed that E6 and E7 in HPV16 upregulated the expression of GLUT1 in lung cancer cells. However, whether they can promote the glucose uptake by GLUT1 and the underlying mole...

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Bibliographic Details
Main Authors: Jia-Yi Tang, Dong-Yu Li, Ling He, Xue-Shan Qiu, En-Hua Wang, Guang-Ping Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
human papillomavirus
glucose transporter 1
lung cancer
glucose uptake
thioredoxin interacting protein
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.559543/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.559543/full

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