Effects of Immediate Aversive Stimulation on Haloperidol-Induced Catalepsy in Rats

Effects of Immediate Aversive Stimulation on Haloperidol-Induced Catalepsy in Rats

In animal models, the administration of the dopaminergic D2 antagonist haloperidol affects the nigrostriatal pathway, inducing catalepsy, a state of immobility similar to Parkinson’s disease (PD) bradykinesia and akinesia. In PD, the motor impairments are due to difficulties in selecting and executi...

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Bibliographic Details
Main Authors: Isabelle Waku, Adriano E. Reimer, Amanda R. de Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
paradoxical kinesia
emotional state
dopamine
D2 antagonist
anxiety
animal model
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.867180/full

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https://www.frontiersin.org/articles/10.3389/fnbeh.2022.867180/full

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