The tumor-stroma ratio in giant cell tumor of bone: associations with the immune microenvironment and responsiveness to denosumab treatment

The tumor-stroma ratio in giant cell tumor of bone: associations with the immune microenvironment and responsiveness to denosumab treatment

Abstract Background Currently, there is limited understanding regarding the clinical significance of the tumor-stroma ratio (TSR) in giant cell tumor of bone (GCTB). Hence, we aimed to investigate the distribution of TSR in GCTB and explore its correlation with various clinicopathologic factors, imm...

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Bibliographic Details
Main Authors: Hai-Lin Wu, Xiao-Bin Wang, Jing Li, Bo-Wen Zheng
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Tumor-stroma ratio
The immune microenvironment
Prognostic biomarker
Denosumab
Giant cell tumor of bone
Online Access:https://doi.org/10.1186/s13018-024-04885-8

Internet

https://doi.org/10.1186/s13018-024-04885-8

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