Neutrophil degranulation and severely impaired extracellular trap formation at the basis of susceptibility to infections of hemodialysis patients

Neutrophil degranulation and severely impaired extracellular trap formation at the basis of susceptibility to infections of hemodialysis patients

Abstract Background Chronic kidney disease patients are at increased risk of mortality with cardiovascular diseases and infections as the two leading causes of death for end-stage kidney disease treated with hemodialysis (HD). Mortality from bacterial infections in HD patients is estimated to be 100...

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Bibliographic Details
Main Authors: Salti Talal, Khoury Mona, Awad Karem, Lerenthal Yaniv, Harari-Misgav Reut, Shemesh Ariel, Avraham-Kelbert Moran, Eitam Harel, Salvatore Campisi-Pinto, Abu-Amna Mahmoud, Colodner Raul, Tovbin David, Bar-Sela Gil, Cohen Idan
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medicine
Subjects:
Neutrophils
Hemodialysis
Infections
Neutrophil degranulation
Neutrophil extracellular traps (NETosis)
Online Access:https://doi.org/10.1186/s12916-022-02564-1

Internet

https://doi.org/10.1186/s12916-022-02564-1

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