Mouse models of surgical and neuropathic pain produce distinct functional alterations to prodynorphin expressing neurons in the prelimbic cortex

Mouse models of surgical and neuropathic pain produce distinct functional alterations to prodynorphin expressing neurons in the prelimbic cortex

The medial prefrontal cortex (mPFC) consists of a heterogeneous population of neurons that respond to painful stimuli, and our understanding of how different pain models alter these specific mPFC cell types remains incomplete. A distinct subpopulation of mPFC neurons express prodynorphin (Pdyn+), th...

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Bibliographic Details
Main Authors: Shudi Zhou, Yuexi Yin, Patrick L. Sheets
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Neurobiology of Pain
Subjects:
Pain models
Prodynorphin
Electrophysiology
Brain slice
Prelimbic cortex
Sex differences
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X23000089

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http://www.sciencedirect.com/science/article/pii/S2452073X23000089

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