Carbamazepine, phenytoin, and oral anticoagulants: Drug‐drug interaction and clinical events in a retrospective cohort

Abstract Background Carbamazepine and phenytoin are potent inducers of enzymes that metabolize oral anticoagulants. Objectives To determine the clinical impact of drug‐drug interactions between these anticonvulsants and oral anticoagulants, and whether they affect the treatment with direct oral anti...

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Bibliographic Details
Main Authors: Matteo Candeloro, John W. Eikelboom, Noel Chan, Vinai Bhagirath, James D. Douketis, Sam Schulman
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12650