PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus.

PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus.

The peroxide response transcriptional regulator, PerR, is thought to contribute to virulence of group A Streptococcus (GAS); however, the specific mechanism through which it enhances adaptation for survival in the human host remains unknown. Here, we identify a critical role of PerR-regulated gene e...

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Bibliographic Details
Main Authors: Ioannis Gryllos, Renata Grifantini, Annalisa Colaprico, Max E Cary, Anders Hakansson, David W Carey, Maria Suarez-Chavez, Leslie A Kalish, Paul D Mitchell, Gary L White, Michael R Wessels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2518855?pdf=render

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http://europepmc.org/articles/PMC2518855?pdf=render

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