PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus.
The peroxide response transcriptional regulator, PerR, is thought to contribute to virulence of group A Streptococcus (GAS); however, the specific mechanism through which it enhances adaptation for survival in the human host remains unknown. Here, we identify a critical role of PerR-regulated gene e...
Main Authors: | Ioannis Gryllos, Renata Grifantini, Annalisa Colaprico, Max E Cary, Anders Hakansson, David W Carey, Maria Suarez-Chavez, Leslie A Kalish, Paul D Mitchell, Gary L White, Michael R Wessels |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-09-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2518855?pdf=render |
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