An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation.

An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation.

Epigenetic mechanisms, including DNA methylation, histone modification, and microRNAs, play pivotal roles in stem cell biology. Methyl-CpG binding protein 1 (MBD1), an important epigenetic regulator of adult neurogenesis, controls the proliferation and differentiation of adult neural stem/progenitor...

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Bibliographic Details
Main Authors: Changmei Liu, Zhao-Qian Teng, Andrea L McQuate, Emily M Jobe, Christa C Christ, Sergei J von Hoyningen-Huene, Marie D Reyes, Eric D Polich, Yina Xing, Yue Li, Weixiang Guo, Xinyu Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547917?pdf=render

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http://europepmc.org/articles/PMC3547917?pdf=render

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