Mammalian nuclear speckles exhibit stable association with chromatin: a biochemical study

Nuclear Speckles (NS) are phase-separated condensates of protein and RNA whose components dynamically coordinate RNA transcription, splicing, transport and DNA repair. NS, probed largely by imaging studies, remained historically well known as Interchromatin Granule Clusters, and biochemical properti...

Full description

Bibliographic Details
Main Authors: Komal Raina, Basuthkar J Rao
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Nucleus
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2021.2024948