Emerging perspectives of synaptic biomarkers in ALS and FTD

Emerging perspectives of synaptic biomarkers in ALS and FTD

Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are debilitating neurodegenerative diseases with shared pathological features like transactive response DNA-binding protein of 43 kDa (TDP-43) inclusions and genetic mutations. Both diseases involve synaptic dysfunction, contribut...

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Bibliographic Details
Main Authors: Karrthik Krishnamurthy, Raj Kumar Pradhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
amyotrophic lateral sclerosis
frontotemporal dementia
synaptic dysfunction
synaptic biomarkers
TDP-43
neuronal pentraxin
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1279999/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2023.1279999/full

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