Targeted Inhibitors of EGFR: Structure, Biology, Biomarkers, and Clinical Applications
Members of the EGFR family of tyrosine kinase receptors are major regulators of cellular proliferation, differentiation, and survival. In humans, abnormal activation of EGFR is associated with the development and progression of many cancer types, which makes it an attractive target for molecular-gui...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/13/1/47 |