Modulation of cell proliferation, survival and gene expression by RAGE and TLR signaling in cells of the innate and adaptive immune response: role of p38 MAPK and NF-KB

Modulation of cell proliferation, survival and gene expression by RAGE and TLR signaling in cells of the innate and adaptive immune response: role of p38 MAPK and NF-KB

Objective: The aim of this study was to evaluate a possible synergism between AGE-RAGE and TLR4 signaling and the role of p38 MAPK and NF-kB signaling pathways on the modulation of the expression of inflammatory cytokines and proliferation of cells from the innate and adaptive immune response. Mat...

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Bibliographic Details
Main Authors: Marcell Costa de MEDEIROS, Sabrina Cruz Tfaile FRASNELLI, Alliny de Souza BASTOS, Silvana Regina Perez ORRICO, Carlos ROSSA JUNIOR
Format: Article
Language:English
Published: University of São Paulo 2014-06-01
Series:Journal of Applied Oral Science
Subjects:
Periodontal diseases
Diabetes mellitus
Innate immunity
Acquired immunity
Advanced glycosylation end products
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000300185&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000300185&lng=en&tlng=en

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