TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy

<p>Abstract</p> <p>Background</p> <p>Redistribution of nuclear TAR DNA binding protein 43 (TDP-43) to the cytoplasm and ubiquitinated inclusions of spinal motor neurons and glial cells is characteristic of amyotrophic lateral sclerosis (ALS) pathology. Recent evidence s...

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Bibliographic Details
Main Authors: Ansorge Olaf, Scaber Jakub, Parkinson Nicholas J, Bäumer Dirk, Turner Bradley J, Talbot Kevin
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/9/104