TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy
<p>Abstract</p> <p>Background</p> <p>Redistribution of nuclear TAR DNA binding protein 43 (TDP-43) to the cytoplasm and ubiquitinated inclusions of spinal motor neurons and glial cells is characteristic of amyotrophic lateral sclerosis (ALS) pathology. Recent evidence s...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/9/104 |