High expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic disease.
HTLV-I-specific CD8(+) T cells have been characterized with high frequencies in peripheral blood and cerebrospinal fluid and production of proinflammatory cytokines, which contribute to central nervous system inflammation in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Howeve...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-12-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC2779586?pdf=render |