SP-8356 (A Verbenone Derivative) Inhibits Proliferation, Suppresses Cell Migration and Invasion and Decreases Tumor Growth of Osteosarcoma: Role of PGC-1α/TFAM and AMPK-Activation

SP-8356 (A Verbenone Derivative) Inhibits Proliferation, Suppresses Cell Migration and Invasion and Decreases Tumor Growth of Osteosarcoma: Role of PGC-1α/TFAM and AMPK-Activation

Objective: Osteosarcoma (OS) is an uncommon sarcoma with osteoid formation in conjunction with malignantmesenchymal cells on histological examination. SP-8356 has been reported to exhibit anti-cancer properties in humancancers. However the impact of SP-8356 on OS is largely unknown. The metabolic pa...

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Bibliographic Details
Main Authors: Wenning Cui, Dengfeng Yang, Xiaoyan Chen, Hong Yu
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2023-05-01
Series:Cell Journal
Subjects:
apoptosis
mice
osteosarcoma
sp-8356
tumor growth
Online Access:https://www.celljournal.org/article_701714_b092a21da80c44ebc15318a226994212.pdf

Internet

https://www.celljournal.org/article_701714_b092a21da80c44ebc15318a226994212.pdf

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