Olanzapine Reverses MK-801-Induced Cognitive Deficits and Region-Specific Alterations of NMDA Receptor Subunits

Olanzapine Reverses MK-801-Induced Cognitive Deficits and Region-Specific Alterations of NMDA Receptor Subunits

Cognitive dysfunction constitutes an essential component in schizophrenia for its early presence in the pathophysiology of the disease and close relatedness to life quality of patients. To develop effective treatment of cognitive deficits, it is important to understand their neurobiological causes a...

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Bibliographic Details
Main Authors: Xiao Liu, Jitao Li, Chunmei Guo, Hongli Wang, Yaxin Sun, Han Wang, Yun-Ai Su, Keqing Li, Tianmei Si
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
MK-801
olanzapine
cognition
schizophrenia
NMDA receptor
prefrontal cortex
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00260/full

Internet

http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00260/full

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