Repeat-mediated epigenetic dysregulation of the FMR1 gene in the Fragile X-related disorders

The Fragile X-related disorders are members of the Repeat Expansion Diseases, a group of genetic conditions resulting from an expansion in the size of a tandem repeat tract at a specific genetic locus. The repeat responsible for disease pathology in the Fragile X-related disorders is CGG/CCG and the...

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Bibliographic Details
Main Authors: Karen eUsdin, Daman eKumari
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00192/full