Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against <it>Staphylococcus aureus</it>, <it>Pseudomonas aeruginosa</it>, and <it>Stenotrophomonas maltophilia</it>

Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against <it>Staphylococcus aureus</it>, <it>Pseudomonas aeruginosa</it>, and <it>Stenotrophomonas maltophilia</it>

<p>Abstract</p> <p>Background</p> <p>Treatment of cystic fibrosis-associated lung infections is hampered by the presence of multi-drug resistant pathogens, many of which are also strong biofilm producers. Antimicrobial peptides, essential components of innate immunity i...

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Bibliographic Details
Main Authors: Pompilio Arianna, Crocetta Valentina, Scocchi Marco, Pomponio Stefano, Di Vincenzo Valentina, Mardirossian Mario, Gherardi Giovanni, Fiscarelli Ersilia, Dicuonzo Giordano, Gennaro Renato, Di Bonaventura Giovanni
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Microbiology
Subjects:
Cystic fibrosis
Antimicrobial peptides
Biofilm
Online Access:http://www.biomedcentral.com/1471-2180/12/145

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http://www.biomedcentral.com/1471-2180/12/145

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