Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

Abstract Background To identify novel epigenetic markers of adolescent asthma and replicate findings in an independent cohort, then explore whether such markers are detectable at birth, predictive of early-life wheeze, and associated with gene expression in cord blood. Methods We performed epigenome...

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Bibliographic Details
Main Authors: Todd M. Everson, Hongmei Zhang, Gabrielle A. Lockett, Akhilesh Kaushal, Melinda Forthofer, Susan L. Ewart, Kimberley Burrows, Caroline L. Relton, Gemma C. Sharp, A. John Henderson, Veeresh K. Patil, Faisal I. Rezwan, S. Hasan Arshad, John W. Holloway, Wilfried Karmaus
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13223-019-0356-z