Analysis of polygenic risk score usage and performance in diverse human populations

Predominant participation of European-ancestry individuals in genetic studies has hindered the better understanding of genetic risk in non-European ancestry individuals. Here, Duncan et al. quantify polygenic risk score use and performance in worldwide populations.

Bibliographic Details
Main Authors: L. Duncan, H. Shen, B. Gelaye, J. Meijsen, K. Ressler, M. Feldman, R. Peterson, B. Domingue
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11112-0