Establishing RTS,S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model

Abstract New strategies are needed to reduce the incidence of malaria, and promising approaches include vaccines targeting the circumsporozoite protein (CSP). To improve upon the malaria vaccine, RTS,S/AS01, it is essential to standardize preclinical assays to measure the potency of next-generation...

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Bibliographic Details
Main Authors: Emily Locke, Yevel Flores-Garcia, Bryan T. Mayer, Randall S. MacGill, Bhavesh Borate, Berenice Salgado-Jimenez, Monica W. Gerber, Shamika Mathis-Torres, Sarah Shapiro, C. Richter King, Fidel Zavala
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00819-x