Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling

Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling

Triple-negative breast cancer (TNBC) accounts for 15% of overall breast cancer. A lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2 receptor) makes TNBC more aggressive and metastatic. Wnt signaling is one of the important pathways in the...

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Bibliographic Details
Main Authors: Dattatrya Shetti, Bao Zhang, Conghui Fan, Canlong Mo, Bae Hoon Lee, Kun Wei
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
breast cancer
XAV939
apoptosis
EMT
pristane
angiogenesis
combination treatment
Wnt signaling
Online Access:https://www.mdpi.com/2073-4409/8/8/892

Internet

https://www.mdpi.com/2073-4409/8/8/892

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