ITGB4/CD104 mediates zika virus attachment and infection

Abstract Zika virus (ZIKV) infection can result in a birth defect of the brain called microcephaly and other severe fetal brain defects. ZIKV enters the susceptible host cells by endocytosis, which is mediated by the interaction of the envelope (E) glycoprotein with cellular surface receptor molecul...

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Bibliographic Details
Main Authors: Haolong Cong, Jiuqiang Wang, Ning Du, Lei Song, Ruigang Wang, Yang Yang, Rong Lei, Tie-Shan Tang, Chang-Mei Liu, Shuifang Zhu, Xiaodong Han
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54479-5