Ultrasound-targeted microbubble destruction optimized HGF-overexpressing bone marrow stem cells to repair fibrotic liver in rats

Ultrasound-targeted microbubble destruction optimized HGF-overexpressing bone marrow stem cells to repair fibrotic liver in rats

Abstract Background/aims Bone marrow mesenchymal stem cells (BMSCs) have shown their therapeutic potential in cytotherapy for liver fibrosis. However, the insufficient homing of BMSCs and undefined proliferation of BMSCs represent a significant challenge and largely limit the effective implementatio...

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Bibliographic Details
Main Authors: Ting Sun, Hualin Li, Yun Bai, Min Bai, Feng Gao, Jie Yu, Rong Wu, Lianfang Du, Fan Li
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Stem Cell Research & Therapy
Subjects:
Liver fibrosis
Liver injury
Bone marrow mesenchymal stem cells
Hepatic growth factor
Ultrasound
Microbubble
Online Access:http://link.springer.com/article/10.1186/s13287-020-01655-1

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http://link.springer.com/article/10.1186/s13287-020-01655-1

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