Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies

A new class of benzimidazole-based derivatives (<b>4a</b>–<b>j</b>, <b>5</b>, and <b>6</b>) with potential dual inhibition of EGFR and BRAF<sup>V600E</sup> has been developed. The newly synthesized compounds were submitted for testing for a...

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Bibliographic Details
Main Authors: Bahaa G. M. Youssif, Martha M. Morcoss, Stefan Bräse, Mohamed Abdel-Aziz, Hamdy M. Abdel-Rahman, Dalal A. Abou El-Ella, El Shimaa M. N. Abdelhafez
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/2/446