The Bacterial Component Flagellin Induces Anti-Sepsis Protection Through TLR-5, IL-1RN and VCAN During Polymicrobial Sepsis in Mice

The Bacterial Component Flagellin Induces Anti-Sepsis Protection Through TLR-5, IL-1RN and VCAN During Polymicrobial Sepsis in Mice

Background: The present study was designed to observe the effects of the bacterial component flagellin on anti-sepsis protection through TLR-5, VCAN and IL-1RN. Methods: A clinically relevant model of sepsis was induced by cecal ligation and puncture (CLP). An in vitro culture of endothelial cells w...

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Bibliographic Details
Main Authors: Jiang Zhu, Guangjie Duan, Lang Lang, Yao Liu, Junmin Zhu, Hu Wang, Yousheng Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Sepsis
Toll-like receptor-5
VCAN
IL-1RN
Flagellin
Online Access:http://www.karger.com/Article/FullText/430111

Internet

http://www.karger.com/Article/FullText/430111

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