YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia
Persistent human papillomavirus (HPV) infection of stratified squamous epithelial cells causes nearly 5% of cancer cases worldwide. HPV-positive oropharyngeal cancers harbor few mutations in the Hippo signaling pathway compared to HPV-negative cancers at the same anatomical site, prompting the hypot...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/75466 |