Membrane protein trafficking in the anti-tumor immune response: work of endosomal-lysosomal system

Abstract Immunotherapy has changed the treatment landscape for multiple cancer types. In the recent decade, great progress has been made in immunotherapy, including immune checkpoint inhibitors, adoptive T-cell therapy, and cancer vaccines. ICIs work by reversing tumor-induced immunosuppression, res...

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Bibliographic Details
Main Authors: Yan Jin, Zhifeng Deng, Ting Zhu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02805-6