Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs
RNA G-quadruplexes (RG4) occur in vivo and have regulatory roles in mRNA metabolism. Here the authors show that the guanine residue stretches at the 5’ end of tRNA-derived stress-induced RNAs mediate the formation of tetramolecular RG4 structures, which play a role in the post-transcriptional regula...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01278-w |