In Silico and In Vitro Search for Dual Inhibitors of the <i>Trypanosoma brucei</i> and <i>Leishmania major</i> Pteridine Reductase 1 and Dihydrofolate Reductase
The parasites <i>Trypanosoma brucei</i> (<i>Tb</i>) and <i>Leishmania major</i> (<i>Lm</i>) cause the tropical diseases sleeping sickness, nagana, and cutaneous leishmaniasis. Every year, millions of humans, as well as animals, living in tropical to su...
Main Authors: | Katharina Possart, Fabian C. Herrmann, Joachim Jose, Thomas J. Schmidt |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/28/22/7526 |
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