Investigation of the genetic etiology in male infertility with apparently balanced chromosomal structural rearrangements by genome sequencing

Investigation of the genetic etiology in male infertility with apparently balanced chromosomal structural rearrangements by genome sequencing

Apparently balanced chromosomal structural rearrangements are known to cause male infertility and account for approximately 1% of azoospermia or severe oligospermia. However, the underlying mechanisms of pathogenesis and etiologies are still largely unknown. Herein, we investigated apparently balanc...

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Bibliographic Details
Main Authors: Matthew Hoi Kin Chau, Ying Li, Peng Dai, Mengmeng Shi, Xiaofan Zhu, Jacqueline Pui Wah Chung, Yvonne K Kwok, Kwong Wai Choy, Xiangdong Kong, Zirui Dong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Journal of Andrology
Subjects:
azoospermia; balanced structural rearrangements; genome sequencing; male infertility; severe oligospermia
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=3;spage=248;epage=254;aulast=Chau

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=3;spage=248;epage=254;aulast=Chau

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