VPPIPP and IPPVPP: two hexapeptides innovated to exert antihypertensive activity.

In this study, two hexapeptides of IPPVPP and VPPIPP were innovated by using two commercial antihypertensive peptides IPP and VPP as two domains cis-linked and trans-linked, respectively. The IPPVPP and VPPIPP were chemically synthesized and evaluated for the antihypertensive activity in vitro/vivo....

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Bibliographic Details
Main Authors: Fengyun Ding, Bingjun Qian, Xin Zhao, Shanqi Shen, Yun Deng, Danfeng Wang, Feng Zhang, Zhongquan Sui, Pu Jing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23638059/?tool=EBI