Engineering of Burkholderia thailandensis strain E264 serves as a chassis for expression of complex specialized metabolites

Engineering of Burkholderia thailandensis strain E264 serves as a chassis for expression of complex specialized metabolites

Heterologous expression is an indispensable approach to exploiting natural products from phylogenetically diverse microbial communities. In this study, we constructed a heterologous expression system based on strain Burkholderia thailandensis E264 by deleting efflux pump genes and screening constitu...

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Bibliographic Details
Main Authors: Zong-Jie Wang, Xiaotong Liu, Haibo Zhou, Yang Liu, Lin Zhong, Xue Wang, Qiang Tu, Liujie Huo, Fu Yan, Lichuan Gu, Rolf Müller, Youming Zhang, Xiaoying Bian, Xiaokun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
Burkholderia
chassis
heterologous expression
disorazol
rhizoxin
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1073243/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1073243/full

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