Obtainment of <i>Threo</i> and <i>Erythro</i> Isomers of the 6-Fluoro-3-(2,3,6,7,8,9-hexahydronaphtho[2,3-<i>b</i>][1,4]dioxin-2-yl)-2,3-dihydrobenzo[<i>b</i>][1,4]dioxine-5-carboxamide

Obtainment of <i>Threo</i> and <i>Erythro</i> Isomers of the 6-Fluoro-3-(2,3,6,7,8,9-hexahydronaphtho[2,3-<i>b</i>][1,4]dioxin-2-yl)-2,3-dihydrobenzo[<i>b</i>][1,4]dioxine-5-carboxamide

2,6-difluorobenzamides have been deeply investigated as antibacterial drugs in the last few decades. Several 3-substituted-2,6-difluorobenzamides have proved their ability to interfere with the bacterial cell division cycle by inhibiting the protein FtsZ, the key player of the whole process. Recentl...

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Bibliographic Details
Main Authors: Valentina Straniero, Lorenzo Suigo, Giulia Lodigiani, Ermanno Valoti
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molbank
Subjects:
2,6-difluorobenzamide
FtsZ inhibitors
nucleophilic aromatic substitution
side product
Online Access:https://www.mdpi.com/1422-8599/2023/1/M1559

Internet

https://www.mdpi.com/1422-8599/2023/1/M1559

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