Cell death in cancer chemotherapy using taxanes

Cancer cells evolve to be refractory to the intrinsic programmed cell death mechanisms, which ensure cellular tissue homeostasis in physiological conditions. Chemotherapy using cytotoxic drugs seeks to eliminate cancer cells but spare non-cancerous host cells by exploring a likely subtle difference...

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Bibliographic Details
Main Authors: Ana P. Xu, Lucy B. Xu, Elizabeth R. Smith, Joshua S. Fleishman, Zhe-Sheng Chen, Xiang-Xi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1338633/full