Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine

Abstract Geriatric animal models are crucial for a better understanding and an improved therapy of age-related diseases. We observed a high mortality of aged mice after anesthesia with a standard dose of ketamine/xylazine, an anesthetic regimen frequently used in laboratory veterinary medicine. C57B...

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Bibliographic Details
Main Authors: Sandra Schuetze, Anja Manig, Sandra Ribes, Roland Nau
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Laboratory Animal Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42826-019-0008-y