Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity.

A novel risk locus at 4q32.2, located between the Nuclear Assembly Factor 1 (NAF1) and Follistatin Like 5 (FSTL5) genes, was associated with increased risk of developing colorectal cancer (CRC), with SNP rs17042479 being the most associated. However, the link between CRC development and the risk loc...

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Bibliographic Details
Main Authors: Josephine B Olsson, Marietta B Gugerel, Stine B Jessen, Jannie Jørgensen, Ismail Gögenur, Camilla Hansen, Lene T Kirkeby, Jørgen Olsen, Ole B V Pedersen, Peter M Vestlev, Katja Dahlgaard, Jesper T Troelsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0274033