Development and in-vitro, in-vivo evaluation of Pioglitazone-loaded polymeric nanoparticles using central composite design surface response methodology
Pioglitazone is a type 2 diabetes drug encapsulated in polymeric nanoparticles using solvent evaporation techniques. In this study, the drug-polymer ratio (A), stirring speed (B), and stirring time (C) were three process parameters that were optimized using a three-factor, three-level Central Compos...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-05-01
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| Series: | OpenNano |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352952023000208 |